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Created with Raphaël 2.1.0 18.12.2015 Filing date 06.07.2017 Validation fee payment 31.01.2018 (A1) Patent application published 23.04.2019 AGEPI application filing date 31.05.2019 (T2) Translation of the validated European patent 30.04.2022 (CES) Cession 15.05.2025 18.12.2025 Valid until 19.12.2026 Renewal fee to be paid until 18.12.2035 Patent will expire on

Patent in force


(210)Number of the EPO application15813831
(220)Filing date of the EPO application2015.12.18
(80)EPO patent specification publication (B)EPB nr. 06/2019, 2019.02.06
(110)EPO patent number3237406
(11)Number of the documentMD 3237406 T2
(21)Number of the applicatione 2017 0225
(71)Name(s) of applicant(s), code of the countryGalapagos NV, BE;
Les Laboratoires Servier, FR;
(72)Name(s) of inventor(s), code of the countryBREBION Franck Laurent, FR;
ALVEY Luke Jonathan, FR;
AMANTINI David, FR;
DEPREZ Pierre Marc Marie Joseph, FR;
GOSMINI Romain Luc Marie, FR;
JARY Helène Marie, FR;
PEIXOTO Christophe, FR;
VARIN Marie Laurence Claire, FR;
DE CEUNINCK Frédéric André, FR;
POP-BOTEZ Iuliana Ecaterina, FR;
(73)Name(s) of owner(s), code of the countryGALAPAGOS NV, BE;
(54)Title of the invention5-[(Piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis
(13)Kind-of-document code T2
(51)International Patent Classification C07D 403/06 (2006.01.01); A61K 31/496 (2006.01.01); A61P 19/02 (2006.01.01); A61P 19/04 (2006.01.01)
(19)CountryBE
(41)Date of publication of the application2018.01.31
(49)Date of publication of the translation of the validated European patent specification2019.05.31
(30)Priority14307129, 2014.12.22, EP
(74)Patent attorney(Procedură) MARGINE Ion, Str. Lomonosov nr. 43, ap. 23, MD-2009, Chişinău, Republica Moldova
 Assignment contract
Nr. şi data deciziei:3861, 14.03.2022
Nr. şi data contractului:3530, 14.03.2022
Cedent(i):GALAPAGOS NV Generaal De Wittelaan L11/A3 2800 Mechelen, BE LES Laboratoires Servier 35, Rue de Verdun 92284 Suresnes, FR
Cesionar(i):GALAPAGOS NV Generaal De Wittelaan L11/A3 2800 Mechelen, BE
(86)International applicationPCT/EP2015/080430, 2015.12.18
(87)International publicationWO 2016/102347, 2016.06.30
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