| (210) | Number of the EPO application | 16778750 |
| (220) | Filing date of the EPO application | 2016.09.30 |
| (80) | EPO patent specification publication (B) | EPB nr. 49/2022, 2022.12.07 |
| (110) | EPO patent number | 3355919 |
| (11) | Number of the document | MD 3355919 T2 |
| (21) | Number of the application | e 2018 0766 |
| (71) | Name(s) of applicant(s), code of the country | Julius-Maximilians-Universität Würzburg, DE; |
| (72) | Name(s) of inventor(s), code of the country | WISCHHUSEN Jörg, DE; HAAKE Markus, DE; DUMMER Reinhard, CH; MEHLING Matthias, CH; SCHÄFER Tina, DE; SELLE Martina, DE; |
| (73) | Name(s) of owner(s), code of the country | Julius-Maximilians-Universität Würzburg, DE; |
| (54) | Title of the invention | Combination therapy using inhibitors of human growth and differentiation factor 15 (GDF-15) and immune checkpoint blockers |
| (13) | Kind-of-document code | T2 |
| (51) | International Patent Classification | A61K 39/395 (2006.01.01); A61K 31/00 (2006.01.01); C07K 16/22 (2006.01.01); C07K 16/28 (2006.01.01); G01N 33/574 (2006.01.01); G01N 33/50 (2006.01.01) |
| (19) | Country | DE |
| (41) | Date of publication of the application | 2018.09.30 |
| (49) | Date of publication of the translation of the validated European patent specification | 2023.02.28 |
| (30) | Priority | 201517531, 2015.10.02, GB; 201607801, 2016.04.29, GB |
| (74) | Patent attorney | (Procedură) SOCOLOVA Sofia, Str. Drumul Viilor nr. 42, bloc 3, ap. 60, MD-2021, Chişinău, Republica Moldova |
| (86) | International application | PCT/EP2016/073520, 2016.09.30 |
| (87) | International publication | WO 2017/055613, 2017.04.06 |