| (210) | Number of the EPO application | 17792230 |
| (220) | Filing date of the EPO application | 2017.09.29 |
| (80) | EPO patent specification publication (B) | EPB nr. 39/2021, 2021.09.29 |
| (110) | EPO patent number | 3519401 |
| (11) | Number of the document | MD 3519401 T2 |
| (21) | Number of the application | e 2019 0875 |
| (71) | Name(s) of applicant(s), code of the country | VERTEX PHARMACEUTICALS INCORPORATED, US; |
| (72) | Name(s) of inventor(s), code of the country | ALCACIO Timothy, US;
BAEK Minson, US;
GROOTENHUIS Peter, US;
HADIDA RUAH Sara Sabina, US;
HUGHES Robert M., US;
KESHAVARZ-SHOKRI Ali, US;
MCAULEY-AOKI Rachel, US;
MCCARTNEY Jason, US;
MILLER Mark Thomas, US;
VAN GOOR Fredrick, US;
ZHANG Beili, US;
ANDERSON Corey, US;
CLEVELAND Thomas, US;
FRIEMAN Bryan A., US;
KHATUYA Haripada, US;
JOSHI Pramod Virupax, US;
KRENITSKY Paul John, US;
MELILLO Vito, US;
PIERRE Fabrice Jean Denis, US;
TERMIN Andreas P., US;
UY Johnny, US;
ZHOU Jinglan, US;
ABELA Alexander Russell, US;
BUSCH Brett Bradley, US;
PARASELLI Prasuna, US;
SIESEL David Andrew, US; |
| (73) | Name(s) of owner(s), code of the country | VERTEX PHARMACEUTICALS INCORPORATED, US; |
| (54) | Title of the invention | Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator |
| (13) | Kind-of-document code | T2 |
| (51) | International Patent Classification | C07D 401/14 (2006.01.01); C07D 471/14 (2006.01.01); C07D 498/14 (2006.01.01); A61K 31/4439 (2006.01.01); A61P 11/12 (2006.01.01) |
| (19) | Country | US |
| (41) | Date of publication of the application | 2019.09.30 |
| (49) | Date of publication of the translation of the validated European patent specification | 2022.02.28 |
| (30) | Priority | 201662402838 P, 2016.09.30, US; 201662410353 P, 2016.10.19, US; 201662415409 P, 2016.10.31, US; 201662419935 P, 2016.11.09, US |
| (74) | Patent attorney | (Procedură) PARASCA Dumitru, str. Eminescu nr. 40, ap. 13, c/p 28, MD-2012, Chişinău, Republica Moldova |
| (86) | International application | PCT/US2017/054611, 2017.09.29 |
| (87) | International publication | WO 2018/064632, 2018.04.05 |