| (11) | Number of the document | 1616 |
| (21) | Number of the application | 96-0211 |
| (22) | Filing date of the application | 1995.01.23 |
| | Date of filing the request for examination | (pe raspunderea solicitantului) 20.01.1999 |
| (71) | Name(s) of applicant(s), code of the country | WARNER-LAMBERT COMPANY, US; |
| (72) | Name(s) of inventor(s), code of the country | BRIDGES, Alexander, James, US; DENNY, William, Alexander, NZ; FRY, David, US; KRAKER, Alan, US; MEYER, Robert, US; REWCASTLE, Gordon William, NZ; THOMPSON, Andrew, Mark, NZ; SHOWALTER, Howard, Daniel,Hollis, US; |
| (73) | Name(s) of owner(s), code of the country | WARNER-LAMBERT COMPANY, US; |
| (54) | Title of the invention | Tricyclic compounds and method of inhibiting the tyrasin kinases receptors of the epidermal growth factor, pharmaceutical composition, methods of preventing the blastocites implantation and mammals treatment |
| (13) | Kind-of-document code | |
| (51) | International Patent Classification | C07D 239/70 (2006.01); C07D 471/04 (2006.01); C07D 471/14 (2006.01); C07D 473/34 (2006.01); C07D 487/04 (2006.01); C07D 491/04 (2006.01); C07D 491/14 (2006.01); C07D 495/04 (2006.01); C07D 498/14 (2006.01); C07D 513/04 (2006.01); C07D 513/14 (2006.01); |
| (19) | Country | US |
| (41) | Date of publication of the application | 1998.04.30 |
| (45) | Date of publication of patent granting decision: | 2001.02.28 |
| (47) | Date of issuance of patent | 2001.12.31 |
| (30) | Priority | 186, 735, 1994.01.25, US; 186, 745, 1994.01.25, US; 358, 352, 1994.12.23, US |
| (74) | Patent attorney | SIMANENKOVA Tatiana, Str. Andrei Doga 2/1, MD-2024, Chişinău, Republica Moldova |
| | Substantive examiner(s) | EGOROV Tamara |
| (85) | Date of introducing the national procedure | 1996.07.26 |
| (86) | International application | PCT/US1995/000911, 1995.01.23 |
| (87) | International publication | WO 1995/19970, 1995.07.27 |
| | Payment for maintenance up to the date | 2003.01.23 |
| | Date of patent termination | 2003.01.23 |
| | Date of publication of the termination of patent, with the right of restoration | 2003.12.31 |
| | Date of publication of the termination of patent, without the right of restoration | 2004.12.31 |