| (11) | Number of the document | 4300 |
| (21) | Number of the application | a 2012 0128 |
| (22) | Filing date of the application | 2012.12.28 |
| | Date of filing the request for examination | (de fond) 28.12.2012 |
| (71) | Name(s) of applicant(s), code of the country | INSTITUTIA PUBLICA UNIVERSITATEA DE STAT DIN MOLDOVA, MD; |
| (72) | Name(s) of inventor(s), code of the country | GULEA Aurelian, MD; JALBA Angela, MD; TAPCOV Victor, MD; SOVA Sergiu, MD; POIRIER Donald, CA; COTOVAIA Aliona, MD; |
| (73) | Name(s) of owner(s), code of the country | UNIVERSITATEA DE STAT DIN MOLDOVA, MD; |
| (54) | Title of the invention | Inhibitor of HepG2 cell proliferation in liver cancer based on chloro-[2-phenyl(pyridine-2-yl)methanone-4-(3-methoxyphenyl)thiosemicarbazono]nickel |
| (13) | Kind-of-document code | |
| (51) | International Patent Classification | C07F 15/04 (2006.01); C07C 49/303 (2006.01); C07C 49/323 (2006.01); C07C 337/08 (2006.01); A61K 31/175 (2006.01); A61K 31/31 (2006.01); A61P 1/16 (2006.01); A61P 35/00 (2006.01); |
| (19) | Country | MD |
| (45) | Date of publication of patent granting decision: | 2014.08.31 |
| (47) | Date of issuance of patent | 2015.03.31 |
| | Substantive examiner(s) | IUSTIN Viorel |
| | Payment for maintenance up to the date | 2017.12.28 |
| | Date of patent termination | 2017.12.28 |
| | Date of publication of the termination of patent, with the right of restoration | 2018.07.31 |
| | Date of publication of the termination of patent, without the right of restoration | 2019.07.31 |