| (210) | Number of the EPO application | 22741050 |
| (220) | Filing date of the EPO application | 2022.06.03 |
| (80) | EPO patent specification publication (B) | EPB nr. 49/2025, 2025.12.03 |
| (110) | EPO patent number | 4346818 |
| (11) | Number of the document | MD 4346818 T2 |
| (21) | Number of the application | e 2024 0382 |
| (71) | Name(s) of applicant(s), code of the country | VERTEX PHARMACEUTICALS INCORPORATED, US; |
| (72) | Name(s) of inventor(s), code of the country | KARKARE Radhika, US;
CHU Cathy, US;
CIRINCIONE Brenda, US;
CORRELL Darin J., US;
DELFF Philip Kaj Harder, US;
DINEHART Kirk Raymond, US;
BENITO GALLO Paloma, US;
HAY Tanya Louise, US;
JIANG Licong, US;
JONES James B., US;
MCCARTY Katie L., US;
METZLER Catherine P., US;
MILLER Jonathan M., US;
PETERSON Mark C., US;
ROOPWANI Rahul, US;
STAROPOLI John F., US; |
| (73) | Name(s) of owner(s), code of the country | VERTEX PHARMACEUTICALS INCORPORATED, US; |
| (54) | Title of the invention | Solid dosage forms and dosing regimens comprising (2r,3s,4s,5r)-4-[[3-(3,4-difluoro-2-methoxy-phenyl)-4,5-dimethyl-5-(trifluoromethyl) tetrahydrofuran-2-carbonyl]amino]pyridine-2-carboxamide |
| (13) | Kind-of-document code | T2 |
| (51) | International Patent Classification | A61K 31/443 (2006.01.01); A61P 23/00 (2006.01.01); A61P 25/02 (2006.01.01); A61P 29/00 (2006.01.01); A61K 9/20 (2006.01.01) |
| (52) | Cooperative Patent Classification | A61K 9/2054 (EP); A61K 9/2013 (EP); A61K 31/443 (EP); A61P 23/00 (EP); A61P 25/02 (EP); A61P 29/00 (EP) |
| (19) | Country | US |
| (41) | Date of publication of the application | 2024.04.30 |
| (49) | Date of publication of the translation of the validated European patent specification | 2026.03.31 |
| (30) | Priority | 202163196933 P, 2021.06.04, US; 202163196937 P, 2021.06.04, US; 202163285197 P, 2021.12.02, US; 202163285201 P, 2021.12.02, US |
| (74) | Patent attorney | (Procedură) CORCODEL Angela, Bd. Ştefan cel Mare nr. 134, Chişinău, Republica Moldova |
| (86) | International application | PCT/US2022/032253, 2022.06.03 |
| (87) | International publication | WO 2022/256708, 2022.12.08 |