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Created with Raphaël 2.1.0 12.01.2017 Opening of the national phase 11.04.2017 Preliminary and substantive examination 30.06.2017 Publication of the PCT application (A2) 28.06.2018 Establishment of the national regular filing 31.07.2018 Publication of the decision of grant (B1) 31.01.2019 Completion of the opposition filing period 28.02.2019 Issuance of patent (C1) 26.05.2024 19.06.2025 Valid until 19.06.2026 Payment of maintenance fee 19.06.2035 Patent expiration date

Patent in force


(11)Number of the document4584
(21)Number of the applicationa 2017 0006
(22)Filing date of the application2015.06.19
 Date of filing the request for examination (de fond) 12.01.2017
(71)Name(s) of applicant(s), code of the countryGILEAD SCIENCES, INC., US;
(72)Name(s) of inventor(s), code of the countryCARRA Ernest A., US; CHEN Irene, US; ZIA Vahid, US;
(73)Name(s) of owner(s), code of the countryGILEAD SCIENCES, INC., US;
(54)Title of the inventionSodium (2R,5S,13aR)-7,9-dioxo-10-((2,4,6-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepin-8-olate
(13)Kind-of-document code
C1, BOPI 02/2019
B1, BOPI 07/2018
A2, BOPI 06/2017
(51)International Patent Classification C07D 498/14 (2006.01); A61K 31/535 (2006.01); A61P 31/18 (2006.01);
(19)CountryUS
(41)Date of publication of the application2017.06.30
(45)Date of publication of patent granting decision:2018.07.31
(47)Date of issuance of patent2019.02.28
(30)Priority62/015245, 2014.06.20, US
(74)Patent attorneyMARGINE Ion, Str. Lomonosov nr. 43, ap. 23, MD-2009, Chişinău, Republica Moldova
 Substantive examiner(s)JOVMIR Tudor, GROSU Viorel
(85)Date of introducing the national procedure2017.01.12
(86)International applicationPCT/US2015/036757, 2015.06.19
(87)International publicationWO 2015/196116 A1, 2015.12.23
 Payment for maintenance up to the date2024.06.19
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/inventions/details/a 2017 0006