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Created with Raphaël 2.1.0 06.10.2017 Formal examination (assignment of filing date) 08.11.2017 Preliminary examination 22.01.2018 Establishment of the national regular filing 24.01.2018 Substantive examination 31.07.2018 Publication of the decision of grant (B1) 31.01.2019 Completion of the opposition filing period 28.02.2019 Issuance of patent (C1) 06.10.2022 Valid until 31.08.2024 Publication of the decision of forfeiture, the term of re-establishment has expired

Patent lapsed


(11)Number of the document4581
(21)Number of the applicationa 2017 0084
(22)Filing date of the application2017.10.06
 Date of filing the request for examination (de fond) 06.10.2017
(71)Name(s) of applicant(s), code of the countryUNIVERSITATEA DE STAT DIN MOLDOVA, MD;
(72)Name(s) of inventor(s), code of the countryGULEA Aurelian, MD; GRAUR Vasilii, MD; TAPCOV Victor, MD;
(73)Name(s) of owner(s), code of the countryUNIVERSITATEA DE STAT DIN MOLDOVA, MD;
(54)Title of the invention2-{[(Prop-2-en-1-ylcarbamothioyl)hydrazino]methyl} pyridinium nitrate compound having human myeloid leukemia HL-60 cell proliferation inhibitor properties
(13)Kind-of-document code
C1, BOPI 02/2019
B1, BOPI 07/2018
(51)International Patent Classification C07C 337/08 (2006.01); C07D 213/48 (2006.01); A61K 31/175 (2006.01); A61P 35/02 (2006.01);
(19)CountryMD
(45)Date of publication of patent granting decision:2018.07.31
(47)Date of issuance of patent2019.02.28
 Substantive examiner(s)GROSU Petru
 Payment for maintenance up to the date2022.10.06
 Date of patent termination2022.10.06
 Date of publication of the termination of patent, with the right of restoration2023.06.30
 Date of publication of the termination of patent, without the right of restoration2024.08.31
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